Recombinant CDK1/Cdc2 Monoclonal Antibody
Product Specifications
Background
CDC2, also named as CDK1, belongs to the protein kinase superfamily. The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of cdc2 at Thr14 and Tyr15. Phosphorylation at Thr14 and Tyr15, resulting in inhibition of cdc2, can be carried out by Wee1 and Myt1 protein kinases.
Abbreviation
CDK1/Cdc2
UniProt
P06493
Host
Rabbit
Reactivity
Human; Rat; Mouse; African green monkey
Immunogen
Recombinant human CDK1/Cdc2 fragment
Target
CDC; CDK; CDKN; cyclin-dependent kinase; P34CDC; CDK1; CDC2; CDC28A; P34CDC2; cyclin-dependent kinase 1; CDKN1; CDC2; CDC28A; cyclin-dependent kinase 1; P34CDC2; cyclin dependent kinase 1874
Clonality
Monoclonal,Recombinant
Clone
A685
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer; Neuroscience; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:50-1:100; IF 1:50-1:100; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
34 kDa
Isotype
IgG, κ
Available Sizes
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