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Recombinant ACTH Monoclonal Antibody

Product Specifications

Background

ACTH, adrenocorticotropic hormone, is a peptide hormone cleavage product of the POMC protein produced by the pituitary gland. ACTH plays an important role in stress and circadian rhythm signaling. Its primary action is on the adrenal cortex, where its binding induces the secretion of glucocorticoid steroid hormones. The peptide sequence for this hormone is highly evolutionarily conserved amongst mammals. Specifically, for mouse and rat, this sequence shares 100% identity.

Abbreviation

ACTH

UniProt

P01189

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Recombinant human ACTH fragment

Target

POMC; ACTH; CLIP; LPH; MSH; NPP; POC; Adrenocorticotropin; alpha-intermedin; alpha-melanocortin; alpha-melanotropin; b-EP; Pro-opiomelanocortin; Corticotropin-lipotropin; Gamma-MSH; Corticotropin; Alpha-MSH; Beta-LPH; Gamma-LPH; Beta-MSH; Beta-endorphin; Met-enkephalin; Melanotropin gamma; Potential peptide; Adrenocorticotropic hormone; Alpha melanocyte stimulating hormone; alphaMSH; Beta LPH; Beta melanocyte stimulating hormone; Corticotropin lipotropin; Corticotropin-like intermediary peptide; Gamma LPH; included; Lipotropin; Lipotropin beta; Lipotropin gamma; Melanocyte-stimulating hormone; Melanotropin; Melanotropin alpha; Melanotropin beta; Opiomelanocortin prepropeptide; Pomc1; Pomc-1; Pomc2; Pro ACTH endorphin; Pro opiomelanocortin; Proopiomelanocortin; Proopiomelanocortin preproprotein; Pro-opiomelanocortin-alpha; Tetracosactide; γ-intermedin; γ-melanocortin; γ-melanotropin; ACTH; Adrenocorticotropin; alpha-MSH; Beta-endorphin; beta-MSH; CLIP; Corticotropin; gamma-MSH; LPH; Melanotropin gamma; Met-enkephalin; MSH; NPP; POC; POMC

Clonality

Monoclonal,Recombinant

Clone

A681

Conjugation

Unconjugated

Applications

IHC

Field of Research

Neuroscience; Signal Transduction; Cancer; Metabolism

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

IHC 1:500-1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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