Recombinant p40 Monoclonal Antibody
Product Specifications
Background
Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.
Abbreviation
P40
UniProt
Q7Z6M1
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human p40 fragment
Target
RAB9P; RAB9P40; RABEPK;40 kDa Rab9 effector protein;8430412M01Rik;9530020d24rik; AV073337; bA65N13.1; C87311; DKFZp686P1077; OTTHUMP00000022126; OTTMUSP00000012898; OTTMUSP00000012899; OTTMUSP00000041318; p40; RAB9 effector p40; Rab9 effector protein with Kelch motifs; RABEK; RABEPK protein; RGD1310612; RP11 65N13.1; RP23-446N16.2
Clonality
Monoclonal,Recombinant
Clone
A677
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cell Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
41 kDa
Observed Molecular Weight
41 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
