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Recombinant Perilipin-2 Monoclonal Antibody

Product Specifications

Background

ADFP also known as ADRP (adipocyte differentiation related protein), adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.

Abbreviation

Perilipin-2

UniProt

Q99541

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human Perilipin-2 fragment

Target

MGC; PLIN; PLIN2; ADFP; ADRP; Adipophilin; Adipose differentiation related protein; Adipose differentiation-related protein; MGC10598; Perilipin 2; Perilipin-2; OSM

Clonality

Monoclonal,Recombinant

Clone

A671

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cardiovascular; Signal Transduction; Cancer; Metabolism

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

48 kDa

Observed Molecular Weight

48 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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