Recombinant PHF2 Monoclonal Antibody
Product Specifications
Background
PHD finger protein 2 (PHF2), also known as JHDM1E (Jumonji C domain-containing histone demethylase 1E) or GRC5, is a 1101 amino acid protein, which contains one JmjC domain and one PHD-type zinc finger. PHF2 belongs to the JHDM1 histone demethylase family and localizes in the nucleus. PHF2 demethylases both histones and non-histione proteins. PHF2 is widely expressed in various tissues and exists as two alternative splicing isoforms. The gene encoding PHF2 lies in the candidate region for hereditary sensory neuropathy type I (HSN1), a disorder characterized by sensory dysfunction.
Abbreviation
PHF2
UniProt
O75151
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human PHF2 fragment
Target
GRC; PHF; CENP; KIAA; PHF2; CENP-35; GRC5; JHDM1E; KDM7C; KIAA0662
Clonality
Monoclonal,Recombinant
Clone
A668
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
121 kDa
Observed Molecular Weight
150 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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