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Recombinant 14-3-3 gamma Monoclonal Antibody

Product Specifications

Background

14-3-3 gamma, also known as YWHAG, is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis.

Abbreviation

14-3-3 gamma

UniProt

P61981

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human 14-3-3 gamma fragment

Target

PPP1R; YWHAG;14-3-3GAMMA; PPP1R170;14 3 3 gamma;14 3 3 protein gamma;14 3 3 protein gamma subtype;14 3 3gamma;14-3-3 protein gamma;1433G;3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide; KCIP 1; KCIP1; KCIP-1; N-terminally processed; Protein kinase C inhibitor protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide

Clonality

Monoclonal,Recombinant

Clone

A667

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

28 kDa

Observed Molecular Weight

28 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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