Recombinant 14-3-3 gamma Monoclonal Antibody
Product Specifications
Background
14-3-3 gamma, also known as YWHAG, is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis.
Abbreviation
14-3-3 gamma
UniProt
P61981
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human 14-3-3 gamma fragment
Target
PPP1R; YWHAG;14-3-3GAMMA; PPP1R170;14 3 3 gamma;14 3 3 protein gamma;14 3 3 protein gamma subtype;14 3 3gamma;14-3-3 protein gamma;1433G;3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide; KCIP 1; KCIP1; KCIP-1; N-terminally processed; Protein kinase C inhibitor protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide
Clonality
Monoclonal,Recombinant
Clone
A667
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
28 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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