Recombinant PKC zeta Monoclonal Antibody
Product Specifications
Background
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
Abbreviation
PKC zeta
UniProt
Q05513
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human PKC zeta fragment
Target
PKC; PRKCZ; PKC-ZETA; PKC2;14-3-3-zetaisoform; AI098070; aPKCzeta; C80388; EC 2.7.11.13; included; KPCZ; nPKC zeta; nPKC-zeta; OTTHUMP00000001368; OTTHUMP00000044160; PKC 2; PKC ZETA; Pkcz; PKC-Z; PKCZETA; PKM-zeta; Protein kinase C zeta; Protein kinase C zeta form; Protein kinase C zeta type; Protein Kinase M Zeta; r14-3-3; R74924; zetaPKC
Clonality
Monoclonal,Recombinant
Clone
A658
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cancer; Cardiovascular
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/JqsMYbZx
Calculated Molecular Weight
68 kDa
Observed Molecular Weight
70 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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