Recombinant beta III Tubulin Monoclonal Antibody
Product Specifications
Background
Beta III Tubulin (TUBB3) is one of six β-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation) . Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS) . Microtubules enriched in β3-tubulin are more dynamic than those composed of other β-tubulin isoforms. Research studies have shown that mutations in the β3-tubulin gene TUBB3 cause ocular motility defects and other nervous system disorders. Furthermore, β3-tubulin is present in neoplastic but not in normal differentiated glial cells. Thus, β3-tubulin is a great neuronal marker.
Abbreviation
Beta III Tubulin
UniProt
Q13509
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human beta III Tubulin fragment
Target
FEOM; beta; CFEOM; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; TUBB4; beta-4; beta Tubulin III; TUBB3; beta 3 tubulin; M (beta) 3; M (beta) 6; MC1R; Neuron specific beta III Tubulin; Neuron-specific class III beta-tubulin; QccE-11995; QccE-15186; TBB3; Tubb 3; Tubulin beta 3; Tubulin beta 3 chain; Tubulin beta 4; Tubulin beta III; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III
Clonality
Monoclonal,Recombinant
Clone
A651
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction; Tags & Cell Markers
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/IUtcMWTV
Calculated Molecular Weight
50 kDa
Observed Molecular Weight
50 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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