Recombinant CD72 Monoclonal Antibody
Product Specifications
Background
CD72 is a type II transmembrane glycoprotein of 39-45 kDa and is expressed as a disulphide-linked homodimer. CD72 is a pan B-cell marker covering the full range of differentiation from the very early stages of B cells to mature surface Ig+ B cells. It is expressed in all stages of B cell development except plasma cells. CD72 is also expressed by dendritic cells, tissue macrophages in the red pulp of the spleen and von Kupffer cells in the liver. CD72 is the ligand for CD5. CD72 is a negative regulator of BCR signaling. Interaction of CD100 with CD72 strictly tunes the strength of BCR signals and is essential for maintaining immunological homeostasis as well as generating a proper immune response.
Abbreviation
CD72
UniProt
P21854
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD72 fragment
Target
B-Cell Differentiation Antigen CD; LYB; CD72; CD72b; LYB2; B-Cell Differentiation Antigen CD72; Lyb-2
Clonality
Monoclonal,Recombinant
Clone
A630
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Stem Cells
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
40 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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