Recombinant MBD2 Monoclonal Antibody
Product Specifications
Background
MBD2, also named as DMTase, binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. It recruits histone deacetylases and DNA methyltransferases. MBD2 acts as transcriptional repressor and plays a role in gene silencing.
Abbreviation
MBD2
UniProt
Q9UBB5
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human MBD2 fragment
Target
MBD; NY-CO; MBD2; DMTase; NY-CO-41; DKFZp586O0821
Clonality
Monoclonal,Recombinant
Clone
A621
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
43, 29 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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