Recombinant Desmoglein 3/PVA Monoclonal Antibody
Product Specifications
Background
Desmoglein 3/PVA is a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. Desmoglein 3 preproprotein is proteolytically processed to generate the mature glycoprotein. Desmoglein 3 has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Abbreviation
Desmoglein 3/PVA
UniProt
P32926
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human Desmoglein 3/PVA fragment
Target
DSG; CDHF; DSG3; CDHF6; PVA; desmoglein 3
Clonality
Monoclonal,Recombinant
Clone
A614
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
108 kDa
Observed Molecular Weight
108, 135 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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