Recombinant MYO1C Monoclonal Antibody

Myosin 1C (MYO1C) is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. The related gene myosin 1E has been referred to as myosin 1C in the literature, but it is a distinct locus on chromosome 19.