Recombinant INSL3 Monoclonal Antibody
Product Specifications
Background
Insulin-like 3 (INSL3), a Leydig cell-specific hormone, is essential for testis descent during foetal life and bone metabolism in adults. Insl3-deficient mice exhibit bilateral undescended testes located high in the abdominal cavity. INSL3 is presumed also to conform to a heterodimeric A-B structure of approximately 6 kDa once released from the producing cells. It is possible that both the mature form of INSL3 (6.6 kDa) and the pro-form (s) of INSL3 (12-14 kDa) are secreted from mammalian Leydig cells.
Abbreviation
INSL3
UniProt
P51460
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human INSL3 fragment
Target
Insulin-like; Insl; Insulin-like 3; Leydig insulin-like peptide; ley-I-L; Relaxin-like factor; RLF; RLNL; INSL3
Clonality
Monoclonal,Recombinant
Clone
A607
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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