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Recombinant KIR3DL1 Monoclonal Antibody

Product Specifications

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against human KIR3DL1and has a molecular weight of 49 kDa.

Abbreviation

KIR3DL1

UniProt

P43629

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human KIR3DL1 fragment

Target

NKB; NKAT; KIR3DL; CD158E; NKAT3; NKB1; KIR3DL1; NKB1; NKB1B; p70; AMB11; CD158 antigen-like family member E; CD158e antigen; CD158E1; CD158E1/2; CD158E2; CL11; CL2; HLA-BW4-specific inhibitory NK cell receptor; KI3L1; killer cell immunoglobulin like receptor; Killer cell immunoglobulin like receptor three domains; Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1; Killer cell immunoglobulin-like receptor 3DL1; KIR; KIR antigen 3DL1; KIR G1; KIR3DS1; Kirl1; Kirl2; Krl1; MGC119726; MGC119728; MGC126589; MGC126591; MHC class I NK cell receptor; Natural killer associated transcript 3; Natural killer cell inhibitory receptor; Natural killer-associated transcript 3; NK receptor; NK-associated transcript 10; NK-associated transcript 3; NK-associated transcript 3delIg1; NKAT10; NKAT-3; NKB1B; p70 killer cell inhibitory receptor; p70 natural killer cell receptor clones CL 2/CL 11; p70 natural killer cell receptor clones CL-2/CL-11; p70 NK receptor CL-2/CL-11; short cytoplasmic tail

Clonality

Monoclonal,Recombinant

Clone

A606

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

49 kDa

Observed Molecular Weight

38 kDa

Isotype

IgG, κ

Available Sizes

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