Recombinant UQCRFS1/RISP Monoclonal Antibody
Product Specifications
Background
Ubiquinol-cytochrome c reductase iron-sulfur subunit (UQCRFS1), also known as Rieske iron-sulfur protein (RISP), is a component of Complex III in the mitochondrial electron transport chain. UQCRFS1/RISP and two other subunits, cytochrome b (MT-CYB) and cytochrome c1 (CYC1), are essential for the catalytic activity of Complex III. Studies show that UQCRFS1/RISP is required for fetal mouse hematopoietic stem cell differentiation and adult mouse hematopoietic stem cell quiescence. In addition, loss of UQCRFS1/RISP decreases the strength of T cell receptor (TCR) signaling, indicating that this protein is critical for optimal TCR signaling.
Abbreviation
UQCRFS1/RISP
UniProt
P47985
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human UQCRFS1/RISP fragment
Target
RIS; RIP; UQCR; UQCRFS; UQCRFS1; RIP1; RIS1; RISP; UQCR5
Clonality
Monoclonal,Recombinant
Clone
A596
Conjugation
Unconjugated
Applications
WB; IHC; IP
Field of Research
Microbiology; Signal Transduction; Cell Biology; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:200-1:1000; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
25 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7181634 Inquire
Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPBC3B9.04 Polyclonal Antibody
Ask
View Details 