Recombinant SLFN11 Monoclonal Antibody
Product Specifications
Background
SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication, leading to cell death.
Abbreviation
SLFN11
UniProt
Q7Z7L1
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human SLFN11 fragment
Target
SLFN8/9; SLFN11
Clonality
Monoclonal,Recombinant
Clone
A582
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
103 kDa
Observed Molecular Weight
103 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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