Recombinant Fibulin-5 Monoclonal Antibody

Fibulin-5, also known as EVEC and DANCE, is an extracellular matrix glycoprotein, secreted by various cell types such as vascular smooth muscle cells, fibroblasts and endothelial cells. Structurally, Fibulin-5 contains an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Fibulin-5 mutations have been described in patients with age-related macular degeneration, as well as being involved in Charcot-Marie-Tooth neuropathies.

UNQ; PRO; FBLN; ADCL; ARMD; fibulin; FBLN5; ADCL2; ARCL1A; ARMD3; DANCE; EVEC; FIBL-5; HNARMD; UP50; fibulin-5; Developmental arteries and neural crest EGF like protein; Developmental arteries and neural crest EGF-like protein; FIBL 5; FLJ90059; Urine p50 protein; UNQ184; PRO210