Recombinant VAV3 Monoclonal Antibody
Product Specifications
Background
Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian VAV proteins (VAV1, VAV2 and VAV3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. VAV2 and VAV3 are more ubiquitously expressed. VAV proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization.
Abbreviation
VAV3
UniProt
Q9UKW4
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human VAV3 fragment
Target
VAV; VAV3
Clonality
Monoclonal,Recombinant
Clone
A556
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
98 kDa
Observed Molecular Weight
98 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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