Recombinant VAV3 Monoclonal Antibody

Product Specifications

Background

Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian VAV proteins (VAV1, VAV2 and VAV3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. VAV2 and VAV3 are more ubiquitously expressed. VAV proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization.

Abbreviation

VAV3

UniProt

Q9UKW4

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human VAV3 fragment

Target

VAV; VAV3

Clonality

Monoclonal,Recombinant

Clone

A556

Conjugation

Unconjugated

Applications

Field of Research

Signal Transduction; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

98 kDa

Observed Molecular Weight

98 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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