Recombinant CD1c Monoclonal Antibody
Product Specifications
Background
CD1c is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1c is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail.
Abbreviation
CD1c
UniProt
P29017
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD1c fragment
Target
CD1C; BDCA-1; R7; T6
Clonality
Monoclonal,Recombinant
Clone
A555
Conjugation
Unconjugated
Applications
WB; IHC; IP
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Observed Molecular Weight
43 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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