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Recombinant IL-4 Monoclonal Antibody

Product Specifications

Background

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.

Abbreviation

IL-4

UniProt

P05112

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant human IL-4 fragment

Target

Interleukin; B-cell growth factor; BSF; IL4; BCGF-1; BCGF1; BSF-1; BSF1; IL-4; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; Binetrakin; IGG1 induction factor; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra; IL2

Clonality

Monoclonal,Recombinant

Clone

A554

Conjugation

Unconjugated

Applications

WB; IF; FCM

Field of Research

Immunology; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IF 1:50; FCM 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

17 kDa

Observed Molecular Weight

14 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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