Recombinant AKT1+AKT2+AKT3 Monoclonal Antibody
Product Specifications
Background
The Akt/PKB family of kinases, Akt1, -2, and -3, plays critical roles in regulating growth, proliferation, survival, metabolism, and other cellular activities. Akt kinases control these activities by phosphorylation-mediated regulation of multiple substrates. Deregulated, or enhanced, Akt signaling has also been implicated in a variety of human cancers, and may promote tumorigenesis.
Abbreviation
AKT1+AKT2+AKT3
UniProt
P31749; P31751; Q9Y243
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human AKT1 + AKT2 + AKT3 fragment
Target
PKB; RAC; PKB beta; PKBG; STK-2
Clonality
Monoclonal,Recombinant
Clone
A549
Conjugation
Unconjugated
Applications
WB; IHC; IF
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56 kDa
Observed Molecular Weight
56 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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