Recombinant Cyclin D2 Monoclonal Antibody
Product Specifications
Background
Cyclin D2 (CCND2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.
Abbreviation
Cyclin D2
UniProt
P30279
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant human Cyclin D2 fragment
Target
CCND; KIAK; MPPH; G1/S-specific cyclin-D; cyclin D; CCND2; KIAK0002; MPPH3; cyclin D2; G1/S-specific cyclin-D2
Clonality
Monoclonal,Recombinant
Clone
A542
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:10000; IHC 1:100-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
36 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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