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Recombinant non-muscle Myosin IIA Monoclonal Antibody

Product Specifications

Background

Non-muscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity. The holoenzyme consists of two identical heavy chains and two sets of light chains. The light chains (MLCs) regulate myosin II activity and stability. The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10, and MYH14, which generate three different non-muscle myosin II isoforms, IIa, IIb, and IIc, respectively.

Abbreviation

Non-muscle Myosin IIA

UniProt

Q8VDD5

Host

Rabbit

Reactivity

Rat; Mouse

Immunogen

Recombinant human non-muscle Myosin IIA fragment

Target

MYH; Myh9

Clonality

Monoclonal,Recombinant

Clone

A541

Conjugation

Unconjugated

Applications

WB; IP

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:200-1:1000; IP 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

237 kDa

Observed Molecular Weight

250 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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