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Recombinant SUV39H2 Monoclonal Antibody

Product Specifications

Background

SUV39H2, also known as KMT1B, is a member of the SUV39 subfamily of lysine methyltransferases (KMTs) that plays a significant role in histone H3-K9 di-/Trimethylation, transcriptional regulation and cell cycle. Overexpressions of SUV39H2 at gene, mRNA and protein levels are known to be associated with a range of cancers: leukemia, lymphomas, lung cancer, breast cancer, colorectal cancer, gastric cancer, hepatocellular cancer and so on. Accumulating evidence indicates that SUV39H2 acts as an oncogene and contributes to the initiation and progression of cancers.

Abbreviation

SUV39H2

UniProt

Q9H5I1

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human SUV39H2 fragment

Target

SUV39H; SUV39H2; KMT1B; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3 K9 methyltransferase 2; Histone H3-K9 methyltransferase 2; Histone lysine N methyltransferase H3 lysine 9 specific 2; Histone lysine N methyltransferase SUV39H2; Histone-lysine N-methyltransferase SUV39H2; Lysine N methyltransferase 1B; Lysine N-methyltransferase 1B; sSuppressor of variegation 3 9 homolog 2 (Drosophila) ; Su (var) 3 9 Drosophila homolog of 2; Su (var) 3 9 homolog 2; Su (var) 3-9 homolog 2; Suppressor of variegation 3 9 homolog 2; Suppressor of variegation 3-9 homolog 2; SUV92

Clonality

Monoclonal,Recombinant

Clone

A529

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

47, 50 kDa

Isotype

IgG, κ

Available Sizes

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