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Recombinant Cdc23 Monoclonal Antibody

Product Specifications

Background

CDC23, also known as APC8, is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16) . APC8 protein associates with APC3 and APC6 to facilitate the recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.

Abbreviation

Cdc23

UniProt

Q9UJX2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant human Cdc23 fragment

Target

CDC; APC; CUT; ANAPC; CDC23; ANAPC8; APC8; CUT23; Anaphase promoting complex subunit 8; Anaphase-promoting complex subunit 8; Apc 8; Cdc 23; cell division cycle 23; Cell division cycle 23 homolog; Cell division cycle protein 23; Cell division cycle protein 23 homolog; Cyclosome subunit 8

Clonality

Monoclonal,Recombinant

Clone

A522

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cell Biology; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/10XSyecx

Calculated Molecular Weight

69 kDa

Observed Molecular Weight

69 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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