Recombinant Cdc23 Monoclonal Antibody
Product Specifications
Background
CDC23, also known as APC8, is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16) . APC8 protein associates with APC3 and APC6 to facilitate the recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.
Abbreviation
Cdc23
UniProt
Q9UJX2
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human Cdc23 fragment
Target
CDC; APC; CUT; ANAPC; CDC23; ANAPC8; APC8; CUT23; Anaphase promoting complex subunit 8; Anaphase-promoting complex subunit 8; Apc 8; Cdc 23; cell division cycle 23; Cell division cycle 23 homolog; Cell division cycle protein 23; Cell division cycle protein 23 homolog; Cyclosome subunit 8
Clonality
Monoclonal,Recombinant
Clone
A522
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cell Biology; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
69 kDa
Observed Molecular Weight
69 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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