Recombinant Pin1 Monoclonal Antibody
Product Specifications
Background
Pin1 is a member of the parvulin family of peptidyl-prolyl isomerases (PPIase) . It has been implicated in the G2/M transition of the mammalian cell cycle. Pin1 is a small (18 kDa) protein with two distinct functional domains: an amino-terminal WW domain and a carboxy-terminal PPlase domain. Pin1 interacts with several mitotic phosphoproteins, including Plk1, cdc25C and cdc27, and is thought to act as a phosphorylation-dependent PPlase for these target molecules.
Abbreviation
Pin1
UniProt
Q9QUR7
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Pin1 fragment
Target
PIN; Pin1
Clonality
Monoclonal,Recombinant
Clone
A517
Conjugation
Unconjugated
Applications
WB; IF; FCM
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:10000; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
18 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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