Recombinant PRK2 Monoclonal Antibody
Product Specifications
Background
PRK2 is a member of the protein kinase C-related kinases (PRKs), a subfamily of Ser/Thr-specific kinases with a catalytic domain highly homologous to the PKC family. PKC-related serine/threonine-protein kinase and Rho/Rac effector protein participate in specific signal transduction responses in the cell. PRK2 plays a role in regulating cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion, and transcription activation signaling processes. Among its related pathways are signaling by Rho GTPases and signaling by GPCR. Gene Ontology (GO) annotations related to this gene include RNA binding and protein kinase activity.
Abbreviation
PRK2
UniProt
Q16513
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human PRK2 fragment
Target
STK; PRO; PKN; PRK; PRKCL; Pak; PAK2; PRK2; PRKCL2; PRO2042; Pak-2; STK7; PKN2
Clonality
Monoclonal,Recombinant
Clone
A515
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cell Biology; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
112 kDa
Observed Molecular Weight
130 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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