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Recombinant PRK2 Monoclonal Antibody

Product Specifications

Background

PRK2 is a member of the protein kinase C-related kinases (PRKs), a subfamily of Ser/Thr-specific kinases with a catalytic domain highly homologous to the PKC family. PKC-related serine/threonine-protein kinase and Rho/Rac effector protein participate in specific signal transduction responses in the cell. PRK2 plays a role in regulating cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion, and transcription activation signaling processes. Among its related pathways are signaling by Rho GTPases and signaling by GPCR. Gene Ontology (GO) annotations related to this gene include RNA binding and protein kinase activity.

Abbreviation

PRK2

UniProt

Q16513

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human PRK2 fragment

Target

STK; PRO; PKN; PRK; PRKCL; Pak; PAK2; PRK2; PRKCL2; PRO2042; Pak-2; STK7; PKN2

Clonality

Monoclonal,Recombinant

Clone

A515

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Cell Biology; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

112 kDa

Observed Molecular Weight

130 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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