Recombinant FGFR3 Monoclonal Antibody
Product Specifications
Background
Fibroblast growth factor receptor 3 is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR proteins are involved in a wide array of pathways known to play a significant role in cancer. Activation of these receptors can lead to activation of the RAS-MAPK pathway and the PI3K-AKT pathway, among others.
Abbreviation
FGFR3
UniProt
P22607
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human FGFR3 fragment
Target
CEK; JTK; Fibroblast growth factor receptor; ACH; CD333; CEK2; HSFGFR3EX; JTK4; FGFR3; FGFR-3; Fibroblast growth factor receptor 3; IIIc; ACH; CD333; FGFR3; Fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; CD 333; CD333 antigen; CEK 2; FGFR 3; Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism) ; Heparin binding growth factor receptor; Hydroxyaryl protein kinase; JTK 4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3
Clonality
Monoclonal,Recombinant
Clone
A492
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Cardiovascular; Signal Transduction; Cancer; Stem Cells
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
88 kDa
Observed Molecular Weight
125 kDa
Isotype
IgG, κ
Available Sizes
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