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Recombinant FGFR3 Monoclonal Antibody

Product Specifications

Background

Fibroblast growth factor receptor 3 is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR proteins are involved in a wide array of pathways known to play a significant role in cancer. Activation of these receptors can lead to activation of the RAS-MAPK pathway and the PI3K-AKT pathway, among others.

Abbreviation

FGFR3

UniProt

P22607

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human FGFR3 fragment

Target

CEK; JTK; Fibroblast growth factor receptor; ACH; CD333; CEK2; HSFGFR3EX; JTK4; FGFR3; FGFR-3; Fibroblast growth factor receptor 3; IIIc; ACH; CD333; FGFR3; Fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; CD 333; CD333 antigen; CEK 2; FGFR 3; Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism) ; Heparin binding growth factor receptor; Hydroxyaryl protein kinase; JTK 4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3

Clonality

Monoclonal,Recombinant

Clone

A492

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Signal Transduction; Cancer; Stem Cells

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:2000; IP 1:25-1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

88 kDa

Observed Molecular Weight

125 kDa

Isotype

IgG, κ

Available Sizes

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