Recombinant CHD3 Monoclonal Antibody
Product Specifications
Background
Chromodomain-helicase-DNA-binding protein 3 (CHD3) is an enzyme that is encoded by the CHD3 gene in human. This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD3 is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Mutations in CHD3 gene cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.
Abbreviation
CHD3
UniProt
Q12873
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant human CHD3 fragment
Target
CHD; CHD3; Mi-2a; Mi2-ALPHA; ZFH; chromodomain helicase DNA binding protein 3
Clonality
Monoclonal,Recombinant
Clone
A479
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Immunology; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/QpKtDQ08
Calculated Molecular Weight
227 kDa
Observed Molecular Weight
260 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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