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Recombinant ELP4 Monoclonal Antibody

Product Specifications

Background

Elongator Acetyltransferase Complex Subunit 4 (ELP4) is a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. The elongator complex catalyzes formation of carboxy methyluridine in the wobble base at position 34 in tRNAs. Diseases associated with ELP4 include Aniridia 2 and Coloboma of Optic Nerve. Among its related pathways are Mesodermal Commitment Pathway and Chromatin organization.

Abbreviation

ELP4

UniProt

Q96EB1

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human ELP4 fragment

Target

ELP; Elongator complex protein; hELP; C11orf; dJ68P15A; dJ68P15A.1; Elongation protein 4 homolog; elongation protein 4 homolog (S. cerevisiae) ; Elongator complex protein 4; FLJ20498; hELP4; PAX6 neighbor gene protein; PAX6NEB; C11orf19; PAXNEB; ELP4; dJ68P15A.1

Clonality

Monoclonal,Recombinant

Clone

A478

Conjugation

Unconjugated

Applications

WB; IF; IP

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IF 1:50; IP 1:25-1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

53, 59kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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