Recombinant MUC13 Monoclonal Antibody
Product Specifications
Background
Mucin 13 (MUC13) is a high-molecular-weight transmembrane glycoprotein that is frequently and aberrantly expressed in a variety of epithelial carcinomas, including gastric, colorectal, and ovarian cancers. On the basis of the high expression of MUC13 in cancer cells as well as recent laboratory findings suggesting a malignant phenotype of MUC13-transfected cell lines, the oncogenic potential of MUC13 has emerged. The various functional domains of MUC13 may confer oncogenic potential to MUC13. MUC13 exhibits the characteristics suitable as an early marker for cancer screening and presents a promising target for antibody-guided targeted therapy.
Abbreviation
MUC13
UniProt
Q9H3R2
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human MUC13 fragment
Target
Muc; UNQ; DRCC; DRCC1; RECC; MUC13; UNQ6194; PRO20221; Down-regulated in colon cancer 1
Clonality
Monoclonal,Recombinant
Clone
A477
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Signal Transduction; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
120, 80, 35 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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