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Recombinant MUC13 Monoclonal Antibody

Product Specifications

Background

Mucin 13 (MUC13) is a high-molecular-weight transmembrane glycoprotein that is frequently and aberrantly expressed in a variety of epithelial carcinomas, including gastric, colorectal, and ovarian cancers. On the basis of the high expression of MUC13 in cancer cells as well as recent laboratory findings suggesting a malignant phenotype of MUC13-transfected cell lines, the oncogenic potential of MUC13 has emerged. The various functional domains of MUC13 may confer oncogenic potential to MUC13. MUC13 exhibits the characteristics suitable as an early marker for cancer screening and presents a promising target for antibody-guided targeted therapy.

Abbreviation

MUC13

UniProt

Q9H3R2

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human MUC13 fragment

Target

Muc; UNQ; DRCC; DRCC1; RECC; MUC13; UNQ6194; PRO20221; Down-regulated in colon cancer 1

Clonality

Monoclonal,Recombinant

Clone

A477

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Signal Transduction; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

55 kDa

Observed Molecular Weight

120, 80, 35 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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