Recombinant CD146 Monoclonal Antibody
Product Specifications
Background
CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread.
Abbreviation
CD146
UniProt
P43121
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human CD146 fragment
Target
MUC; cell surface glycoprotein MUC; MCAM; CD146; MUC18; cell surface glycoprotein MUC18; S-endo; MCAM; Mel-CAM; Endo-CAM; CD146; cell surface glycoprotein MUC18; MUC18; A32 antigen; CD 146; CD146 antigen; Cell surface glycoprotein P1H12; Gicerin; Melanoma adhesion molecule; Melanoma associated antigen A32; Melanoma associated antigen MUC18; Melanoma associated glycoprotein MUC18; melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; MelCAM; MUC 18; S endo 1; S endo 1 endothelial associated antigen; S-endo 1 endothelial-associated antigen
Clonality
Monoclonal,Recombinant
Clone
A472
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Immunology; Signal Transduction; Cancer; Stem Cells; Cardiovascular
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:6000; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72 kDa
Observed Molecular Weight
120 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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