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Recombinant CD146 Monoclonal Antibody

Product Specifications

Background

CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread.

Abbreviation

CD146

UniProt

P43121

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human CD146 fragment

Target

MUC; cell surface glycoprotein MUC; MCAM; CD146; MUC18; cell surface glycoprotein MUC18; S-endo; MCAM; Mel-CAM; Endo-CAM; CD146; cell surface glycoprotein MUC18; MUC18; A32 antigen; CD 146; CD146 antigen; Cell surface glycoprotein P1H12; Gicerin; Melanoma adhesion molecule; Melanoma associated antigen A32; Melanoma associated antigen MUC18; Melanoma associated glycoprotein MUC18; melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; MelCAM; MUC 18; S endo 1; S endo 1 endothelial associated antigen; S-endo 1 endothelial-associated antigen

Clonality

Monoclonal,Recombinant

Clone

A472

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Immunology; Signal Transduction; Cancer; Stem Cells; Cardiovascular

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:6000; IP 1:25-1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

72 kDa

Observed Molecular Weight

120 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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