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Recombinant Thrombomodulin Monoclonal Antibody

Product Specifications

Background

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Abbreviation

Thrombomodulin

UniProt

P07204

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human Thrombomodulin fragment

Target

AHUS; BDCA; THPH; THBD; AHUS6; BDCA3; CD141; THPH12; THRM; TM; Fetomodulin; Thrombomodulin

Clonality

Monoclonal,Recombinant

Clone

A448

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cardiovascular; Stem Cells; Kits; Lysates; Other

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

60 kDa

Observed Molecular Weight

90 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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