Recombinant Thrombomodulin Monoclonal Antibody
Product Specifications
Background
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Abbreviation
Thrombomodulin
UniProt
P07204
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human Thrombomodulin fragment
Target
AHUS; BDCA; THPH; THBD; AHUS6; BDCA3; CD141; THPH12; THRM; TM; Fetomodulin; Thrombomodulin
Clonality
Monoclonal,Recombinant
Clone
A448
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cardiovascular; Stem Cells; Kits; Lysates; Other
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60 kDa
Observed Molecular Weight
90 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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