Recombinant CRMP2 Monoclonal Antibody
Product Specifications
Background
Collapsing response mediator protein 2 (CRMP2 and DPYSL2) is known to be a member of the CRMP family. CRMP2 reportedly functions to regulate synaptic transmission, control MT dynamics, and modulate vesicle trafficking in cells and the developing brain. Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Abbreviation
CRMP2
UniProt
Q16555
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human CRMP2 fragment
Target
N2A; DPYSL; DHPRP; DRP; DPYSL2; CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2; dihydropyrimidinase like 2
Clonality
Monoclonal,Recombinant
Clone
A446
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Neuroscience
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB (cell lysate) 1:500-1:2000; WB (tissue lysate) 1:1000-1:10000; IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62 kDa
Observed Molecular Weight
62-66 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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