Recombinant LSD2/AOF1 Monoclonal Antibody
Product Specifications
Background
LSD2, also known as AOF1, is a Lysine (K) -specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.
Abbreviation
LSD2/AOF1
UniProt
Q8NB78
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human LSD2/AOF1 fragment
Target
AOF; LSD; C6orf; AOF1; C6orf193; LSD2; KDM1B
Clonality
Monoclonal,Recombinant
Clone
A440
Conjugation
Unconjugated
Applications
WB; IF; FCM
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
92 kDa
Observed Molecular Weight
100 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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