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Recombinant LSD2/AOF1 Monoclonal Antibody

Product Specifications

Background

LSD2, also known as AOF1, is a Lysine (K) -specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.

Abbreviation

LSD2/AOF1

UniProt

Q8NB78

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human LSD2/AOF1 fragment

Target

AOF; LSD; C6orf; AOF1; C6orf193; LSD2; KDM1B

Clonality

Monoclonal,Recombinant

Clone

A440

Conjugation

Unconjugated

Applications

WB; IF; FCM

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:2000; IF 1:50; FCM 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

92 kDa

Observed Molecular Weight

100 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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