Recombinant Cdc27 Monoclonal Antibody
Product Specifications
Background
Cell division cycle protein 27 homolog (CDC27) is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Abbreviation
Cdc27
UniProt
P30260
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant human Cdc27 fragment
Target
NUC; APC; CDC; ANAPC; CDC27; ANAPC3; APC3; CDC27Hs; D0S1430E; D17S978E; H-NUC; HNUC; NUC2; Anaphase Promoting Complex 3; Anaphase promoting complex protein 3; Anaphase Promoting Complex Subunit 3; Anaphase-promoting complex subunit 3; APC 3; Cdc 27; CDC27 homolog; Cell Division Cycle 27; Cell division cycle protein 27 homolog; H NUC; Nuc2 homolog
Clonality
Monoclonal,Recombinant
Clone
A438
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Cell Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:200-1:1000; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
92 kDa
Observed Molecular Weight
92 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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