Recombinant DNMT1 Monoclonal Antibody

Dnmt1 is an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities.

MGC; CXXC; DNA methyltransferase; CXXC finger protein 9|DNA methyltransferase; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1; CXXC finger protein 9|DNA methyltransferase 1; DNA methyltransferase 1; FLJ16293; MGC104992; ADCADN; AIM; CXXC9; DNA methyltransferase 1; DNMT; HSN1E; m.HsaI; MCMT; CXXC finger protein 9; CXXC-type zinc finger protein 9; DNA (cytosine 5) methyltransferase 1; DNA (cytosine-5) -methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase M.HsaI.; DNA MTase; DNA MTase HsaI; DNMT 1; Dnmt1o; Met1; mMmul; MommeD2