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Recombinant SBDS Monoclonal Antibody

Product Specifications

Background

This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located.

Abbreviation

SBDS

UniProt

Q9Y3A5

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human SBDS fragment

Target

CGI; SBDS; CGI-97; SDS; SWDS

Clonality

Monoclonal,Recombinant

Clone

A432

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:200-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

29 kDa

Observed Molecular Weight

29 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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