Recombinant S100A8 Monoclonal Antibody

MRP8/S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. MRP8 has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic. The extracellular functions involve proinflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration.

Protein S100-A; S100a; Kcnip; KCHIP; MRP; S100A8;60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8; Calgranulin A; Calgranulin-A; Cystic fibrosis antigen; Leukocyte L1 complex light chain; MRP-8; Protein S100-A8; CALP; KCNIP4; KCHIP4; AI323541; B8Ag; BEE11; Calprotectin; Calprotectin L1L subunit; Chemotactic cytokine CP-10; included; Migration inhibitory factor-related protein 8; Myeloid-related protein 8; Neutrophil cytosolic 7 kDa protein; Pro-inflammatory S100 cytokine; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A) ; S100 calcium-binding protein A8; S100A8/S100A9 complex; S10A8; Urinary stone protein band A