Recombinant Na+/K+ ATPase alpha-1 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Abbreviation
Na+/K+ ATPase alpha-1
UniProt
P05023
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Na+/K+ ATPase alpha-1 fragment
Target
ATPase Na+/K+ transporting subunit alpha; HOMGSMR; ATP1A1; ATPase Na+/K+ transporting subunit alpha 1; ATP1A; CMT2DD; HOMGSMR2; A1A1; AT1A1; Atpa-1; ATPase Na+/K+ transporting alpha 1 polypeptide; BC010319; EC 3.6.3.9; K ATPase alpha 1 subunit; K+ ATPase alpha subunit; MGC3285; MGC38419; MGC51750; Na K ATPase alpha A catalytic polypeptide; Na K ATPase catalytic subunit alpha A protein; Na (+) /K (+) ATPase 1; Na (+) /K (+) ATPase alpha-1 subunit; Na+; Na+/K+ ATPase alpha 1 subunit; Na+/K+ ATPase 1; Nkaa1b; Sodium potassium ATPase alpha 1 polypeptide; Sodium pump 1; Sodium pump subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-1
Clonality
Monoclonal,Recombinant
Clone
A420
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Tags & Cell Markers; Signal Transduction; Neuroscience; Cancer; Metabolism; Isotype; Loading Controls
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
113 kDa
Observed Molecular Weight
113 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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