Recombinant ABAT Monoclonal Antibody
Product Specifications
Background
4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. This gene is located in chromosome 16 at position of 13.2. This gene goes by a number of names, including, GABA transaminase, GABAT, 4-aminobutyrate transaminase, NPD009 etc. This gene is mainly and abundant located in neuronal tissues. 4-Aminobutyrate aminotransferase belongs to group of pyridoxal 5-phosphate-dependent enzyme which activates a large portion giving reaction to amino acids. ABAT is made up of two monomers of enzymes where each subunit has a molecular weight of 50kDa. It is identified that almost tierce of human synapses have GABA. GABA is a neurotransmitter that has different roles in different regions of the central and peripheral nervous systems. It can be found also in some tissues that do not have neurons. In addition, GAD and GABA-AT are responsible in regulating the concentration of GABA.
Abbreviation
ABAT
UniProt
P80404
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human ABAT fragment
Target
NPD; ABAT; GABA-AT; GABAT; NPD009
Clonality
Monoclonal,Recombinant
Clone
A395
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Neuroscience; Signal Transduction; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/kbyEd60L
Calculated Molecular Weight
56 kDa
Observed Molecular Weight
50 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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