Recombinant WWOX Monoclonal Antibody
Product Specifications
Background
Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF) -mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Abbreviation
WWOX
UniProt
Q9NZC7
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human WWOX fragment
Target
PRO; WOX; EIEE; SCAR; HHCMA; SDR41C; WWOX; D16S432E; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1;5330426P09Rik;9030416C10Rik; Aberrant WW domain-containing oxidoreductase; EC 1.1.1.-; Fragile site FRA16D oxidoreductase; Fragile site FRA16D Oxireductase; member 1; MGC55975; Putative oxidoreductase; Short chain dehydrogenase/reductase family 41C; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; zgc:55975
Clonality
Monoclonal,Recombinant
Clone
A392
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Cell Biology; Neuroscience; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100; IF 1:200-1:500; FCM 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47 kDa
Observed Molecular Weight
47 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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