Recombinant RMP/C19orf2 Monoclonal Antibody
Product Specifications
Background
Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.
Abbreviation
RMP/C19orf2
UniProt
O94763
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human RMP/C19orf2 fragment
Target
NNX; PPP1R; C19orf; C19orf2; NNX3; PPP1R19; RMP; URI; URI1; prefoldin-like chaperone; Chromosome 19 open reading frame 2; NNX3; NNX3 protein; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RMP; RNA polymerase II subunit 5 mediating protein; RNA polymerase II subunit 5-mediating protein; RPB5 mediating protein; RPB5-mediating protein; Unconventional prefoldin RPB5 interactor; Unconventional prefoldin RPB5 interactor 1
Clonality
Monoclonal,Recombinant
Clone
A386
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60 kDa
Observed Molecular Weight
79 kDa
Isotype
IgG, κ
Available Sizes
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