Recombinant TMPRSS2 Monoclonal Antibody
Product Specifications
Background
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells.
Abbreviation
TMPRSS2
UniProt
O15393
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant human TMPRSS2 fragment
Target
PRSS; TMPRSS; TMPRSS2; PP9284; PRSS10
Clonality
Monoclonal,Recombinant
Clone
A380
Conjugation
Unconjugated
Applications
WB; IHC; FCM
Field of Research
Neuroscience; Cell Biology; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54 kDa
Observed Molecular Weight
52 kDa
Isotype
IgG, κ
Available Sizes
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