Recombinant Thyroglobulin Monoclonal Antibody
Product Specifications
Background
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) . The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.
Abbreviation
Thyroglobulin
UniProt
P01266
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human Thyroglobulin fragment
Target
TDH; TG; AITD3; TGN; AITD 3; hTG; TDH3; THYG; Thyroglobulin; AITD 3; AITD3; hTG; TDH3; Tg; TGN; THYG; Thyroglobulin
Clonality
Monoclonal,Recombinant
Clone
A378
Conjugation
Unconjugated
Applications
IHC; FCM
Field of Research
Signal Transduction; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:100-1:1000; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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