Recombinant SIGIRR Monoclonal Antibody
Product Specifications
Background
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Abbreviation
SIGIRR
UniProt
Q9JLZ8
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant human SIGIRR fragment
Target
Tir; Tir8; Sigirr
Clonality
Monoclonal,Recombinant
Clone
A360
Conjugation
Unconjugated
Applications
WB
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
80 kDa
Isotype
IgG, κ
Available Sizes
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